Tedavi Ddr Capsules 60Mg (1 Strip = 10 Capsules)

Requires Prescription: Yes

Generics: Dexlansoprazole

Used For: Gastroesophageal Reflux Disease (GERD)

How It Works:

Dexlansoprazole is a proton pump inhibitor that belongs to the class of substituted benzimidazoles. It suppresses gastric acid secretion by specifically inhibiting the (H+, K+)-ATPase at the secretory surface of the gastric parietal cells, effectively blocking the final step of acid production.

Tedavi Ddr Usage and Safety:

Dosage:

Dexlansoprazole

Side Effects:

Common: Diarrhea, abdominal pain, nausea, upper respiratory tract infection, vomiting, flatulence

Less Common: Anemia, lymphadenopathy, angina, arrhythmia, bradycardia, chest pain, edema, myocardial infarction, palpitation, tachycardia, ear pain, tinnitus, vertigo, goiter, eye irritation, eye swelling, abdominal discomfort, abdominal tenderness, abnormal feces, anal discomfort, Barrett’s esophagus, bezoar, abnormal bowel sounds, breath odor, microscopic colitis, colonic polyp, constipation, dry mouth, duodenitis, dyspepsia, dysphagia, enteritis, eructation, esophagitis, gastric polyp, gastritis, gastroenteritis, gastrointestinal disorders

Drug Interactions:

Rilpivirine, atazanavir, nelfinavir, saquinavir

Warfarin

Methotrexate

Digoxin

Iron salts

Erlotinib, dasatinib, nilotinib, mycophenolate mofetil

Ketoconazole, itraconazole

Tacrolimus

Tetrahydrocannabinol (THC)

CYP2C19 or CYP3A4 inducers (e.g., St. John’s Wort, rifampin)

CYP2C19 or CYP3A4 inhibitors (e.g., voriconazole)

Indication:

Healing of all grades of erosive esophagitis (EE) for up to eight weeks

Maintenance of EE healing and relief of heartburn for up to six months

Treatment of heartburn associated with symptomatic non-erosive GERD for four weeks

When Not to Use:

Dexlansoprazole is contraindicated in:

Patients with known hypersensitivity to dexlansoprazole or any of its excipients

Individuals using rilpivirine-containing products

Patients with severe hepatic impairment

Tedavi Ddr Precautions:

Precaution:

Proton pump inhibitors (PPIs) may increase the risk of Clostridium difficile-associated diarrhea, particularly in hospitalized patients. Use the lowest effective dose and shortest duration necessary for the condition being treated.

Tedavi Ddr Warnings:

Warning 1:

Long-term PPI therapy may increase the risk of osteoporosis-related bone fractures of the hip, spine, or wrist. Use the lowest effective dose and shortest duration necessary. Manage patients at risk for fractures according to established treatment guidelines.

Warning 2:

Consider checking serum magnesium levels before starting long-term therapy, especially if taking digoxin, diuretics, or other drugs known to cause hypomagnesemia.

Warning 3:

Prolonged use of dexlansoprazole may lead to vitamin B12 malabsorption and deficiency. Monitor vitamin B12 levels if treatment extends beyond one year.

Additional Information:

Pregnancy Category:

Always consult your physician before using any medicine.

Storage:

Store at room temperature, away from direct light and heat.