Requires Prescription: Yes
Generics: Omeprazole
Used For: Gastroesophageal Reflux Disease (GERD)
How It Works: Omeprazole inhibits gastric acid secretion by irreversibly blocking the hydrogen/potassium adenosine triphosphatase (H+/K+ ATPase) enzyme system, also known as the proton pump, in gastric parietal cells. This effect is dose-dependent and leads to the suppression of both basal and stimulated acid secretion, regardless of the stimulus.
Omezol Capsules Usage and Safety:
Dosage: As prescribed by your healthcare provider.
Side Effects:
Common:
Central and Peripheral Nervous System: Headache.
Gastrointestinal: Diarrhea, constipation, abdominal pain, nausea/vomiting, flatulence.
Uncommon:
Central and Peripheral Nervous System: Dizziness, paraesthesia, somnolence, insomnia, vertigo.
Hepatic: Increased liver enzymes.
Skin: Rash, pruritus, urticaria.
Other: Malaise.
Rare:
Central and Peripheral Nervous System: Reversible mental confusion, agitation, aggression, depression, hallucinations (mainly in severely ill patients).
Endocrin: Gynecomastia.
Drug Interactions: Potential interactions with ketoconazole, itraconazole, diazepam, citalopram, imipramine, clomipramine, phenytoin, atazanavir, digoxin, clopidogrel, posaconazole, erlotinib, saquinavir, tacrolimus, methotrexate, clarithromycin, and drugs affecting CYP2C19 or CYP3A4 (e.g., rifampicin, St. John’s Wort).
Indication:
Treatment of GERD in adults, including:
Erosive reflux esophagitis.
Long-term management to prevent relapse in patients with healed esophagitis.
Symptomatic treatment of GERD.
When Not to Use: Contraindicated in patients with known hypersensitivity to any component of the formulation or substituted benzimidazoles. Not to be used with nelfinavir.
Omezol Capsules Precautions:
Precaution: Omeprazole, like other acid-blocking medications, may impair the absorption of vitamin B12 (cyanocobalamin) due to reduced stomach acid. This should be monitored in patients with low body stores or risk factors for vitamin B12 deficiency during long-term use.
Omezol Capsules Warnings:
Gastric Malignancy: If gastric ulcer is suspected, malignancy should be ruled out as treatment may alleviate symptoms and delay diagnosis.
Fracture Risk: Prolonged use of proton pump inhibitors, especially in high doses and for over one year, may modestly increase the risk of fractures of the hip, wrist, and spine, particularly in the elderly or those with other risk factors.
Hepatic Function: Dose adjustment may be necessary in patients with impaired hepatic function due to increased bioavailability and prolonged half-life.
Additional Information:
Pregnancy Category: Always consult your physician before using any medication.
Storage: Store at room temperature, away from direct light and heat.
Reviews
There are no reviews yet.