Novomix 50 Specification
Requires Prescription (YES/NO)
Yes
Generics
Insulin Aspart , Protamine Insulin Aspart
Used For
Diabetes Management
How it works
NovoMix 50 is a biphasic insulin, which contains 50% soluble insulin aspart. This has a rapid onset of action, thus allowing it to be given closer to a meal (within zero to 10 minutes of the meal) when compared to soluble human insulin. The crystalline phase (50%) consists of protamine-crystallised insulin aspart, which has an activity profile similar to that of human NPH insulin. When NovoMix 50 is injected subcutaneously, the onset of action will occur within 10 to 20 minutes of injection. The maximum effect is exerted between 1 and 4 hours after injection. The duration of action is 14 to 24 hours
Novomix 50 Usage And Safety
Dosage
Insulin Aspart , Protamine Insulin Aspart
Side Effects
• The most common side effect when using insulin is low blood sugar levels (a hypo). • Mild to moderate Other effects: • pain, redness, hives, bruising, swelling or itching at the injection site.Usually these symptoms disappear within a few weeks during continued use. If you have serious or continuing reactions, you may need to stop using NovoRapid® and use another insulin.• a depression or thickening of the skin around the injection site (lipodystrophy).• lumps under your skin (cutaneous amyloidosis).• when you first start your insulin treatment you may get visual problems or swollen hands and feet.
Drug Interactions
The following substances may reduce the patient’s insulin requirements:Oral antidiabetic medicinal products, GLP-1 receptor agonists, monoamine oxidase inhibitors (MAOI), beta-blockers, angiotensin converting enzyme (ACE) inhibitors, salicylates, anabolic steroids and sulfonamides.The following substances may increase the patient’s insulin requirements:Oral contraceptives, thiazides, glucocorticoids, thyroid hormones, sympathomimetics, growth hormone and danazol.Beta-blockers may mask the symptoms of hypoglycaemia.Octreotide/lanreotide may either increase or decrease the insulin requirement.Alcohol may intensify or reduce the hypoglycaemic effect of insulin.
Indication
NovoMix 50 FlexPen is used to treat diabetes mellitus .
When not to Use
Hypersensitivity to the active substance or to any of the excipient .
Novomix 50 Precautions
Precaution
NovoMix 50 must not be administered intravenously, as it may result in severe hypoglycaemia. Intramuscular administration should be avoided. NovoMix 30 is not to be used in insulin infusion pumps.
Novomix 50 Warnings
Warning 1
If you are blind or have poor eyesight and cannot read the dose counter on the pen, do not use this pen without help. Get help from a person with good eyesight who is trained to use NovoMix® 30 FlexPen®.
Warning 2
Inform your doctor as soon as possible if you experience signs of heart failure such as unusual shortness of breath or rapid increase in weight or localised swelling (oedema). Some patients with long-standing type 2 diabetes mellitus and heart disease or previous stroke who are treated with thiazolidinediones in combination with insulin may develop heart failure.
Warning 3
Inadequate dosing or discontinuation of treatment, especially in type 1 diabetes, may lead to hyperglycaemia and diabetic ketoacidosis. Usually, the first symptoms of hyperglycaemia develop gradually over a period of hours or days. They include thirst, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, dry mouth, loss of appetite as well as acetone odour of breath. In type 1 diabetes, untreated hyperglycaemic events eventually lead to diabetic ketoacidosis, which is potentially lethal.
Novomix 50 Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store in a refrigerator (2°C–8°C). Do not Freeze .
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