Requires Prescription: Yes
Generics: Rabeprazole Sodium
Used For: Acidity & Ulcers
How It Works: Rabeprazole is a proton pump inhibitor (PPI) that suppresses gastric acid secretion by inhibiting the H+ /K+ ATPase enzyme at the parietal cells of the stomach. It does not affect anticholinergic or histamine H2-receptor pathways but effectively reduces both basal and stimulated gastric acid production.
Usage and Safety:
Dosage: As prescribed by your healthcare provider.
Side Effects:
Common: Headache, diarrhea, nausea.
Other Adverse Events: Rhinitis, abdominal pain, asthenia, flatulence, pharyngitis, vomiting, non-specific pain/back pain, dizziness, flu-like symptoms, infection, cough, constipation, insomnia.
Less Frequent: Rash, myalgia, chest pain, dry mouth, dyspepsia, nervousness, somnolence, bronchitis, sinusitis, chills, eructation, leg cramps, urinary tract infection, arthralgia, fever.
Rare: Anorexia, gastritis, weight gain, depression, pruritus, vision or taste disturbances, stomatitis, sweating, leucocytosis, thrombocytopenia, neutropenia, leukopenia.
Drug Interactions: May interact with ketoconazole or itraconazole.
Indication: Used for treating:
Active duodenal ulcers
Active benign gastric ulcers
Symptomatic erosive or ulcerative gastroesophageal reflux disease (GERD)
When Not to Use:
Contraindicated in patients with hypersensitivity to rabeprazole, other substituted benzimidazoles, or any component of the product.
Not recommended during pregnancy or breastfeeding.
Not recommended for children due to lack of experience in this age group.
Precautions:
Rule out malignancy before starting treatment with rabeprazole, as symptomatic improvement does not exclude the presence of gastric or esophageal cancer.
Patients on long-term treatment (especially those treated for over a year) should be regularly monitored.
Warnings:
Use with caution in patients with severe hepatic dysfunction.
During pregnancy, use only if clearly necessary and after discussing the risks and benefits with your doctor.
Long-term use of proton pump inhibitors like rabeprazole may increase the risk of bone fractures, especially with higher doses and in older adults.
Additional Information:
Pregnancy Category: Consult your physician before use.
Storage: Store at room temperature, away from direct light and heat.
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