Gravinate Tablets 50Mg (1 Strip = 10 Tablets)

Requires Prescription: No

Generics: Dimenhydrinate

Used For: Vomiting relief

How it works: Dimenhydrinate’s antiemetic, anti-motion sickness, and antivertigo effects are not fully understood. It may work through central anticholinergic actions and affect the medullary chemoreceptor trigger zone. Additionally, it may inhibit vestibular stimulation, initially affecting the otolith system and, at higher doses, the semicircular canals.

Gravinate Tablets Usage and Safety:

Dosage: Follow the prescribed dosage instructions.

Side Effects:

Headache

Dry mouth

Difficulty urinating

Drowsiness, feeling less alert, somnolence (mainly observed in early treatment)

Vertigo

Myasthenia (muscle weakness)

Increased intraocular pressure

Balance problems

Memory or concentration difficulties (more common in the elderly)

Confusion

Hallucinations

Difficulty sleeping

Difficulty moving

Involuntary muscle movements

Drug Interactions:

CNS depressants (e.g., tranquilizers, hypnotics, anxiolytics)

Monoamine oxidase inhibitors (MAOIs)

Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)

CYP2D6 substrates (e.g., metoprolol, venlafaxine)

Indication: Used for the prevention and relief of nausea, vomiting, and/or vertigo.

When Not to Use:

Hypersensitivity to dimenhydrinate, diphenhydramine, 8-chlorotheophylline, or any component of the formulation.

During or within two weeks following treatment with a monoamine oxidase inhibitor.

Patients with narrow-angle glaucoma.

Patients with chronic lung disease.

Gravinate Tablets Precautions

Precaution: Use with caution in patients with:

Myasthenia gravis

Epilepsy or seizure disorders

Prostatic hypertrophy

Urinary retention

Narrow-angle glaucoma

Asthma, bronchitis, and chronic obstructive pulmonary disease (COPD)

Moderate to severe hepatic or renal impairment

Gravinate Tablets Warnings:

Warning 1: Tolerance may develop with continuous use. Consult your doctor if sleeplessness persists, as it may indicate a serious underlying condition.

Warning 2: Avoid using other antihistamine-containing preparations, including topical antihistamines and cough/cold medicines.

Warning 3: Use with caution in the elderly due to a higher risk of side effects.

Gravinate Tablets Additional Information:

Pregnancy Category: Always consult your physician before using this medication.

Storage: Store at room temperature, away from direct light and heat.