Description
The mechanism of action of Ammonium Chloride and Guaifenesin Syrup/Suspension is as follows Ammonium Chloride works by increasing the pH of the urine, making it more acidic, which helps to dissolve and eliminate certain types of urinary tract stones and crystals. This action also helps to relieve the discomfort associated with urinary tract conditions. Guaifenesin, on the other hand, is an expectorant that increases the hydration of respiratory tract secretions, reducing their viscosity. This thinning effect helps to loosen and break down mucus in the airways, making it easier to cough up and clear the respiratory tract. Guaifenesin stimulates the release of water and mucus from the respiratory tract, thereby reducing the thickness and stickiness of mucus, and improving its clearance from the lungs.
Ingredients
Ammonium Chloride, Guaifenesin
Drug Class
Expectorant, Mucus thinning agent.
Dosage Form
Suspension
Uses
The following are the uses of Ammonium Chloride, Guaifenesin Syrup/Suspension:
- Used for relieving chest congestion caused by the common cold, acute bronchitis, or other respiratory illnesses.
- Used for loosening and thinning mucus, making it easier to cough up.
- Used to reduce coughing and soothe irritated throats.
- Used for treating minor aches and pains associated with the cold and flu.
- Used for reducing fever and relieving headaches.
- Used in certain cases to treat allergies and sinus congestion.
- Used as an expectorant to help clear airways and improve breathing.
- Used to provide temporary relief from symptoms, allowing for better rest and recovery.
Dosage
Take as per doctor’s prescription
In case of Overdose
In the case of an overdose of Ammonium Chloride or Guaifenesin Syrup/Suspension, individuals may experience specific symptoms related to the medication’s properties. Ammonium Chloride overdose can lead to gastrointestinal issues like nausea, vomiting, and abdominal pain, while an excessive amount of Guaifenesin Syrup/Suspension may result in dizziness, headache, and increased heart rate. Seeking medical advice is essential to manage these symptoms effectively.
Missed Dose
In the case of a missed dose of Ammonium Chloride, administer the missed dose as soon as you remember, but if it’s almost time for the next dose, skip the missed dose and continue with your regular dosing schedule. For Guaifenesin Syrup/Suspension, if a dose is missed, take it as soon as possible and then adjust the remaining doses accordingly, ensuring you do not double the dose to make up for the missed one. It is important to follow the prescribed schedule closely for maximum effectiveness.
How To Use
To take Ammonium Chloride and Guaifenesin Syrup/Suspension, shake the bottle well, then use the provided measuring device to draw the prescribed amount, and swallow the medication as directed, typically twice a day, regardless of meals, following the dosage instructions provided by your healthcare professional.
When Not to Use
Here are the conditions or situations when Ammonium Chloride, Guaifenesin Syrup/Suspension should not be used:
- Do not use in patients with a known allergy or hypersensitivity to ammonium chloride or guaifenesin.
- Contraindicated in individuals with severe kidney disease or kidney failure.
- Not suitable for patients with severe lung diseases or difficulty breathing.
- Avoid in patients with hereditary fructose intolerance as it may contain sweeteners.
- Should not be used in patients with a history of stomach ulcers or gastrointestinal bleeding.
- Do not administer to infants or young children without medical advice.
- Contraindicated in patients with a history of bronchospasm or asthma.
- Not recommended for individuals with a history of seizures or epilepsy.
Side Effects
The side effects of Ammonium Chloride, Guaifenesin Syrup/Suspension may include:
- Nausea and vomiting
- Stomach pain or cramps
- Diarrhea
- Dizziness or lightheadedness
- Skin rash or itching
- Increased sweating
- Dry mouth
- Cough or throat irritation
Precautions & Warnings
Following are the precautions and warnings for Ammonium Chloride, Guaifenesin Syrup/Suspension:
- Do not use this medication if you have a known allergy to Ammonium Chloride or Guaifenesin or any other ingredients in the syrup.
- Patients with underlying medical conditions like asthma, chronic bronchitis, or emphysema should use with caution and under medical supervision.
- Avoid using this medication if you have a persistent cough, as it may indicate a more serious condition. Seek medical advice in such cases.
- Do not exceed the recommended dosage, as it may lead to severe side effects, including increased heart rate and blood pressure.
- Consult a doctor if you have a history of kidney stones, as Ammonium Chloride may increase the risk of stone formation.
- Guaifenesin may cause dizziness or drowsiness, so avoid driving or operating heavy machinery until you know how this medication affects you.
- Pregnant and breastfeeding women should consult their healthcare provider before taking this medication, as the effects on the fetus or infant are not fully established.
Drug Interactions
Following are the drug interactions for Ammonium Chloride, Guaifenesin Syrup/Suspension:
- May interact with other cough suppressants or expectorants, leading to reduced effectiveness of Guaifenesin.
- Antacids containing aluminum or calcium can decrease the absorption of Ammonium Chloride.
- Theophylline levels may be increased when used with Guaifenesin, requiring monitoring.
- Use with caution alongside diuretics, as it may increase the risk of electrolyte imbalances.
- May reduce the effectiveness of medications containing iodine, such as potassium iodide.
- Ammonium Chloride can increase the risk of methenamine-induced crystalluria.
- Guaifenesin may interact with certain antibiotics, affecting their absorption and effectiveness.
Food Interactions
Following are the food interactions for Ammonium Chloride, Guaifenesin Syrup/Suspension:
- Avoid consuming excessive amounts of salty or highly acidic foods, as Ammonium Chloride is used to treat excess stomach acid and may interact with these foods.
- Grapefruit and grapefruit juice should be consumed with caution as they can affect the metabolism of Guaifenesin, leading to increased levels in the body and potential side effects.
- Avoid alcohol as it can irritate the throat and reduce the effectiveness of Guaifenesin, which is used to relieve coughs.
- Avoid caffeinated beverages as they can increase stomach acid production, counteracting the effects of Ammonium Chloride.
- Dairy products may increase mucus production, which could affect the action of Guaifenesin, so consider reducing intake during treatment.
- Spicy foods may cause throat irritation and coughing, potentially reducing the effectiveness of Guaifenesin.
- Stay well-hydrated by drinking plenty of water to help Guaifenesin loosen and thin mucus, making it easier to expel.
- No significant food interactions directly impact the absorption of these medications, but always follow healthcare provider instructions.
Storage/Disposal
Ammonium Chloride and Guaifenesin Syrup/Suspension should be stored in a controlled environment, preferably in a cool and dry place away from direct sunlight and moisture. It is crucial to maintain the integrity of the medication by keeping it tightly sealed in its original packaging. Avoid exposing it to extreme temperatures, including heat sources like radiators or ovens, as this can impact its effectiveness. Regularly check the expiration date, and if the medication is no longer needed or has expired, dispose of it responsibly. Do not dispose of it in household waste or pour it down the drain; instead, consult a pharmacist or healthcare professional for guidance on proper disposal. Ensure that the medication is kept securely away from children to prevent accidental consumption.
Control Drug
Yes
Quick Tips, if any
Following are the quick tips for Ammonium Chloride and Guaifenesin Syrup/Suspension:
- Consult a healthcare professional for dosage instructions, especially for children.
- Always measure the dose accurately using a measuring device.
- Take the medication as directed, usually with a full glass of water.
- Do not crush or chew extended-release tablets.
- Avoid taking with dairy products or antacids, as they may interfere with absorption.
- If you miss a dose, take it as soon as you remember, unless it’s close to the next dose.
- Store the medication at room temperature, away from light and moisture.
- Keep a record of your medication usage and refill your prescription as needed.


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