Lornoxicam 8mg Tablet is a non-steroidal anti-inflammatory drug (NSAID) that primarily exerts its analgesic, anti-inflammatory, and antipyretic effects by inhibiting the enzyme cyclooxygenase (COX). It selectively blocks the COX-2 enzyme, which is responsible for the formation of prostaglandins, key mediators of pain, inflammation, and fever. By inhibiting COX-2, lornoxicam reduces the production of prostaglandins, thereby decreasing inflammation, pain sensitivity, and body temperature. This mechanism of action makes lornoxicam effective in managing conditions characterized by pain and inflammation, without directly affecting the COX-1 enzyme, which is involved in maintaining gastric protection and platelet function.
Ingredients
Lornoxicam 8mg
Drug Class
Nonsteroidal anti-inflammatory drug (NSAID)
Dosage Form
Tablet
Uses
The following are the uses of Lornoxicam 8mg Tablet:
- Used for relieving pain and reducing inflammation in conditions like arthritis, gout, and post-operative pain.
- Used to treat acute pain, including dental pain and pain after accidents or injuries.
- Used in managing chronic pain associated with long-term conditions.
- Helps reduce swelling and stiffness, improving mobility in affected joints.
- Effective in providing short-term relief from pain and inflammation.
- Used to ease pain and inflammation in conditions affecting the musculoskeletal system.
Dosage
Dose to be taken as per doctor’s prescription (dependant on the severity of condition, age and weight)
In case of Overdose
In the case of an overdose of Lornoxicam 8mg Tablets, immediate medical intervention is necessary. Symptoms may include severe stomach pain, nausea, and vomiting. Medical professionals should be informed about the overdose, as they may administer activated charcoal to absorb the excess medication. Prompt treatment can help manage and reduce the severity of these symptoms, ensuring the patient’s well-being. It is crucial to seek medical assistance without delay to address the potential risks associated with an overdose.
Missed Dose
In the case of a missed dose of Lornoxicam 8mg Tablet, it is generally advised to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one. If you frequently miss doses, inform your healthcare professional, as they may provide guidance on how to manage missed doses and ensure the medication’s effectiveness.
How To Use
To take Lornoxicam 8mg Tablet, swallow the tablet whole with a glass of water, preferably with or after food, as directed by your doctor, typically once or twice a day, following the dosage instructions provided by your healthcare professional.
When Not to Use
Following are the conditions/situations when Lornoxicam 8mg Tablet should not be taken:
- Avoid if you have a known allergy or hypersensitivity to Lornoxicam or other non-steroidal anti-inflammatory drugs (NSAIDs).
- Do not use if you have active gastrointestinal bleeding or a history of recurrent gastrointestinal bleeding.
- Contraindicated in individuals with severe heart failure or heart attack.
- Should not be taken by individuals with severe liver or kidney impairment.
- Not recommended for patients with a history of aspirin-induced asthma or other respiratory reactions.
- Avoid if you have a history of severe allergic reactions, especially to other medications.
- Do not use if you have recently undergone coronary artery bypass graft (CABG) surgery.
- Contraindicated in patients with bleeding disorders or those on anticoagulant therapy.
- Should not be taken during the last trimester of pregnancy.
Side Effects
The side effects of Lornoxicam 8mg Tablet may include:
- Stomach pain or discomfort
- Nausea and vomiting
- Diarrhea
- Dizziness or vertigo
- Headaches
- Skin rashes or itching
- Increased blood pressure
- Fatigue
Precautions & Warnings
Following are the precautions and warnings for Lornoxicam 8mg Tablet:
- Not recommended for individuals with a history of allergic reactions to NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) or aspirin.
- Patients with gastrointestinal problems, such as ulcers, bleeding, or inflammatory bowel disease, should use with caution as it may worsen these conditions.
- Renal function should be monitored during long-term treatment, especially in elderly patients and those with pre-existing kidney issues.
- Not recommended for patients with severe heart failure or uncontrolled hypertension as it may worsen these conditions.
- Should be used with caution in patients with a history of asthma or allergic disorders, as it may trigger bronchospasm.
- May cause dizziness or drowsiness, so patients should avoid driving or operating heavy machinery until they know how the medication affects them.
- Consult a doctor before use if you are pregnant, planning to become pregnant, or breastfeeding, as it may have potential risks for the fetus or infant.
Drug Interactions
Following are the drug interactions for Lornoxicam 8mg Tablet:
- Avoid using with other non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, as it may increase the risk of gastrointestinal bleeding and kidney problems.
- Concomitant use with diuretics can reduce their natriuretic effect and increase the risk of kidney toxicity.
- Lornoxicam may increase the plasma concentration of lithium, potentially leading to lithium toxicity.
- Probenecid can increase the plasma concentration of Lornoxicam, possibly enhancing its effects and side effects.
- May interact with anticoagulants, increasing the risk of bleeding. Close monitoring is necessary.
- Use with corticosteroids or other immunosuppressants may increase the risk of infection and mask the signs of infection.
- Caution is advised when using with ACE inhibitors or angiotensin II receptor blockers, as it may decrease their antihypertensive effect.
Food Interactions
Following are the food interactions for Lornoxicam 8mg Tablet:
- Avoid excessive alcohol consumption as it can increase the risk of gastrointestinal bleeding and liver toxicity.
- Grapefruit and grapefruit juice should be consumed with caution as they may alter the drug’s metabolism, potentially affecting its effectiveness.
- High-fat meals can delay the absorption of Lornoxicam, so it is advisable to take the medicine on an empty stomach.
- Avoid caffeine-rich foods and beverages, as they may increase the risk of nervousness, insomnia, and gastrointestinal irritation.
- Dairy products like milk and yogurt may interfere with the absorption of Lornoxicam, so it is best to separate their consumption by a few hours.
- Avoid foods rich in vitamin K, such as leafy green vegetables, as they can counteract the blood-thinning effects of Lornoxicam.
- Limit the intake of salt and salty foods, as Lornoxicam may cause sodium and water retention, leading to swelling and increased blood pressure.
- Inform your healthcare provider about any herbal supplements or natural remedies you take, as some may interact with Lornoxicam, reducing its efficacy or increasing side effects.
Storage/Disposal
Lornoxicam 8mg Tablets should be stored in a secure and dry location, preferably in a medicine cabinet or designated storage area, away from direct sunlight, moisture, and heat. Keep the tablets in their original packaging or container, ensuring the lid is tightly sealed to maintain their integrity. It is crucial not to remove the medication from its blister pack unless you are about to take a dose. Do not store lornoxicam in the bathroom or kitchen, as these areas may expose the medication to humidity and temperature fluctuations. Always check the expiration date, and if the tablets have passed their expiry, do not use them and dispose of them safely. Proper disposal methods include returning the medication to a pharmacy or following local guidelines for pharmaceutical waste disposal. Keep the medication out of children’s reach to prevent accidental consumption.


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