Ampiclox Neonatal Specification
Requires Prescription (YES/NO)
Yes
Generics
Ampicillin , Cloxacillin
Used For
Bacterial Infection
How it works
Both ampicillin and cloxacillin are bactericidal antibiotics and act by interfering with the formation of new bacterial cell wall by dividing organisms.
Ampiclox Neonatal Usage And Safety
Dosage
Ampicillin , Cloxacillin
Side Effects
Hemolytic anemia, leucopenia, thrombocytopenia, agranulocytosis , Anaphylaxis , Myoclonus and convulsions , Diarrhoea and nausea , Vomiting , Pseudomembranous colitis , Hepatitis and cholestatic jaundice , Skin rash, urticaria, and pruritus , Bullous reactions (including erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis), exfoliative dermatitis and purpura .
Drug Interactions
Probenecid , Oral contraceptives , Sulphonamides and acetylsalicylic acid , Bacteriostatic drugs , allopurinol
Indication
It is indicated for the treatment of the following infections including mixed Grampositive (except methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant coagulase-negative staphylococcus (MRCoNS)) and Gram-negative infections.
When not to Use
It should not be given to patients with a history of hypersensitivity to beta-lactam antibiotics (e.g., penicillins, cephalosporins) or excipients . It is contraindicated for ocular administration.
Ampiclox Neonatal Precautions
Precaution
It should be avoided if infectious mononucleosis and/or acute or chronic leukaemia of lymphoid origin are suspected. The occurrence of a skin rash has been associated with these conditions following the administration of ampicillin.
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