Description
This medicine is used to treat acidity and ulcers. It contains Vonoprazan, which is a Potassium Competitive Acid Blocker. It works by inhibiting the binding of Potassium ions to the proton pumps, thereby reducing gastric acid production and providing relief.
Ingredients
VonoprazanDrug Class
Potassium Competitive Acid Blockers
Dosage Form
TabletUses
This medication is used to treat:
- Gastric ulcer
- Duodenal ulcer
- Reflux esophagitis
- Preventing gastric or duodenal ulcer recurrence during low-dose aspirin and non-steroidal anti-inflammatory drug (NSAID) administration
Dosage
Follow these dosage instructions or as prescribed by your doctor:
- Gastric & Duedonal Ulcer
20mg daily administered orally for 8 weeks in case of gastric ulcer and 6 weeks for duodenal ulcer.
- Reflux esophagitis
20mg daily administered orally for 4 weeks
- Prevention of the Recurrence of Ulcer
10mg daily administered orally.
In case of Overdose
There is no experience of overdose with Vonoprazan. Vonoprazan is not removed from the circulation by hemodialysis. If an overdose occurs, treatment should be symptomatic and supportive.
Missed Dose
If you miss a dose, make sure to take it as soon as possible the same day. If you don’t remember missing the dose, don’t double it. Consult your doctor on how to adjust the missing doses.
How To Use
Take the tablets daily, with or without food as your doctor has recommended. Take the medication regularly and simultaneously each day to get the most benefit from it.
When Not to Use
Vonoprazan is contraindicated in:
- Patients with hypersensitivity to Vonoprazan or to any excipient of the products.
- Patients receiving atazanavir sulfate, nelfinavir, or rilpivirine hydrochloride.
Side Effects
Common side effects may include:
- Diarrhea
- Constipation
- Drug hypersensitivity (including anaphylactic shock)
- Drug eruption
- Urticaria
- Hepatotoxicity
- Jaundice
- Skin rash
- Nausea
- Abdominal distension
- Liver function test abnormal
Precautions & Warnings
Follow these precautions and warnings before starting the medication:
- Talk to your doctor if you have any allergic reaction or known hypersensitivity to any medicine components.
- If you are pregnant or a lactating mother, talk to your doctor before using this medicine.
- If you have severe liver or kidney impairment, talk to your doctor before starting this medication. Since the hepatic and renal functions are significantly decreased in elderly patients, Vonoprazan should be administered carefully.
Drug Interactions
The following drugs may interact with this medicine:
- CYP3A4 inhibitors Clarithromycin
- Digoxin
- Methyldigoxin
- Itraconazole
- Tyrosine kinase inhibitors
- Gefitinib
- Nilotinib
- Erlotinib
Food Interactions
For Vonoprazan, food interactions that should be considered are:
- Taking before meals may enhance absorption.
Storage/Disposal
Store the medicine at room temperature (not above 30 degrees) and keep out of direct sunlight, excessive heat, and moisture. Keep the medicine out of the reach of children and animals. Do not use the medication past its expiration date.
Control Drug
No
Quick Tips, if any
Complete the full course of therapy and strictly adhere to the doctor’s recommendations.


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