Perispa Tablets Specification
Requires Prescription (YES/NO)
Yes
Generics
Eperisone HCl
Used For
Muscle Relaxant
How it works
1.Skeletal muscle relaxation(1) Inhibition of experimentally-induced muscle rigidity Eperisone hydrochloride suppresses intercollicular section-induced decerebrate rigidity (?-rigidity) and ischemic decerebrate rigidity (a-rigidity) in rats dose-dependently. (2) Suppression of spinal reflexes In spinal cats, eperisone hydrochloride suppresses mono and poly-synaptic reflex potentials induced through spinal nerve efferent root stimulation to a similar degree. (3) Reduction of muscle spindle sensitivity via ?-motor neurons Eperisone hydrochloride suppresses the activity of afferent nerve fibers (Ia fibers) from human muscle spindles at 20 min after administration. Eperisone hydrochloride suppresses the spontaneous discharge of ?-motor neurons, but does not act directly on muscle spindles in animals. Accordingly, eperisone hydrochloride reduces muscle spindle sensitivity via the ?-motor neurons.
Perispa Tablets Usage And Safety
Dosage
Eperisone HCl
Side Effects
Rash , Anemia , Proteinuria and Elevation of BUN, Pruritus , erythema exudativum multiforme , Sleepiness, insomnia, headache and numbness in the extremities , Nausea/vomiting, anorexia, stomach discomfort, abdominal pain, diarrhea, constipation and thirst .
Drug Interactions
Methocarbamol
Indication
Improvement of myotonic conditions caused by the following diseases: Neck-shoulder-arm syndrome, scapulohumeral periarthritis and low back pain· Spastic paralysis caused by the following diseases: Cerebrovascular disorders, spastic spinal paralysis, cervical spondylosis, sequela of surgical trauma (including cerebrospinal tumor), sequela of trauma (spinal injury and head injury), amyotrophic lateral sclerosis, infantile cerebral palsy, spinocerebellar degeneration, spinal vascular disorders, subacute myelo-optico neuropathy (SMON) and other encephalomyelopathies .
When not to Use
Patients with a history of hypersensitivity to any ingredients in the list.
Perispa Tablets Precautions
Precaution
Weakness, light-headedness, sleepiness or other symptoms may occur. In the event of such symptoms, the dosage should be reduced or treatment discontinued. Patients should be cautioned against engaging in potentially hazardous activities requiring alertness, such as operating machinery or driving a car .
Perispa Tablets Warnings
Warning 1
Careful Administration it should be administered with care in the patients with a history of drug hypersensitivity .
Warning 2
Careful Administration it should be administered with care in the patients with hepatic function disorder .
Warning 3
Since the elderly often have a physiological hypofunction, it is advisable to take measures, such as reduction in dosage under careful supervision.
Perispa Tablets Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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