Introduction
Navidoxine tablet is a medication contains a combination of meclizine and vitamin b6. Meclizine is an antihistamine medicine used to manage nausea, vomiting, and vertigo caused by travel sickness. It works by blocking the histamine receptors in the brain. Vitamin b6, also known as pyridoxine, is a water-soluble vitamin that is essential for the metabolism of protein, carbohydrates, and fats. It also assist to lessen nausea and vomiting.
Uses of navidoxine tablet
Navidoxine tablet is used to treat nausea and vomiting caused by motion sickness and morning sickness during pregnancy. Navidoxine tablet is also used to treat other conditions such as vertigo, meniere’s disease, and vestibular disorders that cause dizziness and balance problems.
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Drug interactions
The drug interactions of navidoxine tablet include:
- Antihistamines: taking navidoxine tablet with other antihistamines can increase the risk of side effects such as drowsiness, dizziness, and dry mouth.
- Sedatives: navidoxine tablet can enhance the sedative effects of other medications such as tranquilizers, sleeping pills, and muscle relaxants.
- Monoamine oxidase inhibitors (maois): combining navidoxine tablet with maois can increase blood pressure and cause other serious side effects.
- Levodopa: navidoxine tablet may decrease the effectiveness of levodopa, a medication used to treat parkinson’s disease.
- Pyridoxine supplements: taking navidoxine tablet with high doses of pyridoxine supplements may increase the risk of side effects such as numbness, tingling, and nerve damage.
Disease interactions
Some of the disease interactions of navidoxine tablet include:
- Asthma: meclizine, one of the active ingredients in navidoxine tablet, can cause bronchospasm in patients with asthma or chronic obstructive pulmonary disease (copd).
- Glaucoma: meclizine can increase intraocular pressure and worsen symptoms of glaucoma, a condition characterized by increased pressure in the eyes.
- Liver disease: patients with liver disease may be at increased risk of adverse effects of vitamin b6, such as liver damage.
- Parkinson’s disease: meclizine can interfere with the effectiveness of levodopa, a medication used to treat parkinson’s disease.
- Seizure disorders: meclizine can lower the seizure threshold and increase the risk of seizures in patients with epilepsy or other seizure disorders.
Food interactions
There are no known food interactions with navidoxine tablet. However, it is suggested to grasp the medication with food or milk to lessen the risk of stomach trouble. Additionally, it is important to avoid alcohol while taking navidoxine tablet, as it can increase the risk of side effects such as drowsiness, dizziness, and impaired coordination. It is also recommended to avoid consuming grapefruit or grapefruit juice while taking navidoxine tablet, as it can increase the levels of meclizine in the bloodstream and increase the risk of side effects.
Side effects of navidoxine tablet
Some of the usual side effects of navidoxine tablet include:
- Drowsiness
- Dizziness
- Dry mouth
- Blurred vision
- Constipation
- Nervousness
- Headache
- Insomnia
- Increased heart rate
Less usual side effects of navidoxine tablet may include:
- Rash
- Itching
- Hives
- Swelling of the face, tongue, or throat
- Difficulty breathing
Dosing information
- The dosing information for navidoxine tablet varies depending on the condition being treated and the age of the patient. The usual recommended dose for adults is one tablet (25 mg meclizine hcl and 50 mg pyridoxine hcl) taken orally 1 to 2 times per day, or as directed by a healthcare professional.
- For pregnant women experiencing nausea and vomiting, the recommended dosage is one tablet taken at bedtime. If necessary, a second tablet may be taken 12 hours later.
Precautions and warnings
Here are some precautions and warnings o navidoxine tablets are written below,
- Never take navidoxine tablet if you are suffering from asthma
- Never take navidoxine tablet if you are suffering from heart problems
- Never take navidoxine tablet if you are suffering from glaucoma
- Never take navidoxine tablet if you are suffering from seizures
- Never take navidoxine tablet if you are suffering from stomach problems
- Never take navidoxine tablet during breastfeeding.
Storage
Navidoxine tablets should be stored at room temperature, between 15-30°c (59-86°f), in a dry place away from moisture, heat, and direct sunlight. It is important to keep away navidoxine tablets out of reach of children and pets of the family.
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Packaging
- Navidoxine tablets are available in various packaging sizes, depending on the manufacturer and the country where the medication is sold. Typically, navidoxine tablets come in blister packs, which are individual plastic or foil packets that contain one or more tablets.
- The blister pack is designed to protect the tablets from moisture, light, and air, which can affect the stability and effectiveness of the medication. The blister pack also helps to ensure that each tablet is properly labeled with the name of the medication, the dosage, and the expiration date.
- Navidoxine tablets may also be packaged in a bottle, which is a larger container that holds multiple tablets. The bottle is typically made of plastic or glass and has a child-resistant cap to prevent accidental ingestion by children.
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