Minirin Tablets Specification

Requires Prescription (YES/NO)

Yes

Generics

Desmopressin Acetate

Used For

Diabetes

How it works

By mimicking the actions of endogenous ADH, desmopressin acts as a selective agonist of V2 receptors expressed in the renal collecting duct (CD) to increase water re-absorption and reduce urine production.

Minirin Tablets Usage And Safety

Dosage

Desmopressin Acetate

Side Effects

• Unusually bad or prolonged headache, confusion, unexplained weight gain, ankle swelling, nausea or vomiting • itching, skin rashes, swelling of the face, lips or throat, difficulty in breathing, wheeziness, chest tightness or coughing (signs of allergic reaction) • headache • stomach pain

Drug Interactions

NSAIDs , tricyclic antidepressants, selective serotonin reuptake inhibitors, chlorpromazine and carbamazepine

Indication

It is indicated for the treatment of central diabetes insipidus ; it is also indicated for the treatment of primary nocturnal enuresis in children aged 5 years or more.

When not to Use

It is contraindicated in cases of: – Habitual or psychogenic polydipsia ; A history of known or suspected cardiac insufficiency and other conditions that requiring treatment with diuretics ; Moderate and severe renal insufficiency (creatinine clearance below 50 ml/min) ; Known hyponatraemia

Minirin Tablets Precautions

Precaution

Precautions must be taken in patients at risk of increased intracranial pressure .

Minirin Tablets Warnings

Warning 1

Caution should be exercised in patients with other causes of urinary frequency (e.g. multiple sclerosis or urge incontinence), and in diabetes mellitus and renal impairment, since the use of desmopressin has not been well studied in these populations .

Warning 2

Treatment with desmopressin should be interrupted during acute intercurrent illnesses characterised by fluid and/or electrolyte imbalance (such as systemic infections, fever, gastroenteritis).

Warning 3

It should not be administered to dehydrated or overhydrated patients until water balance has been adequately restored.

Minirin Tablets Additional Information

Pregnancy category

Always consult your physician before using any medicine.

Storage (YES/NO)

Store this medicine at room temperature, away from direct light and heat.