Requires Prescription: Yes
Generics: Esomeprazole
Used For: Acidity & Ulcers
How it Works: Esomeprazole inhibits the proton pump (H+/K+ ATPase) in the stomach’s parietal cells, which significantly reduces hydrochloric acid secretion and alters gastric pH.
Lomac Capsules Usage and Safety:
Dosage: Esomeprazole
Side Effects: Common side effects include headache, gastrointestinal upset, skin reactions, and dry mouth. Rarely, angioedema, anaphylaxis, and fundic gland polyps may occur.
Drug Interactions: Interacts with phenytoin, warfarin, clopidogrel, ketoconazole, itraconazole, voriconazole, diazepam, citalopram, imipramine, clomipramine, CYP3A4 inhibitors or inducers, tacrolimus, digoxin, erlotinib, and methotrexate.
Indication: Used for treating heartburn, gastroesophageal reflux disease (GERD), gastritis, and ulcers.
When Not to Use: Contraindicated in patients with hypersensitivity to proton pump inhibitors (PPIs). Hypersensitivity reactions such as angioedema, anaphylaxis, bronchospasm, acute interstitial nephritis, and urticaria have been reported.
Lomac Capsules Precautions:
Precaution: Long-term use (more than 3 years) may lead to malabsorption or deficiency of cyanocobalamin (vitamin B12).
Lomac Capsules Warnings:
Warning 1: Rare cases of hypomagnesemia have been reported with prolonged PPI therapy.
Warning 2: Extended use or high doses of PPIs may increase the risk of osteoporosis-related fractures of the hip, wrist, or spine.
Warning 3: Avoid using esomeprazole concurrently with clopidogrel.
Additional Information:
Pregnancy Category: Always consult your physician before using any medicine.
Storage: Store at room temperature, away from direct light and heat.
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