Requires Prescription (YES/NO): Yes
Generics: Esomeprazole
Used For: Acidity & Ulcers
How It Works: Esomeprazole works by binding irreversibly to the H+/K+ ATPase in the proton pump. Since this is the final pathway for the secretion of hydrochloric acid by the parietal cells in the stomach, its inhibition significantly decreases the secretion of hydrochloric acid and alters gastric pH.
Esomax Capsules Usage And Safety:
Dosage: Esomeprazole
Side Effects: Headache, GI upset, skin reactions, dry mouth. Rare side effects include angioedema, anaphylaxis, and fundic gland polyps.
Drug Interactions: Esomeprazole may interact with Phenytoin, Warfarin, Clopidogrel, Ketoconazole, Itraconazole, Voriconazole, Diazepam, Citalopram, Imipramine, Clomipramine, CYP3A4 inhibitors or inducers, Tacrolimus, Digoxin, Erlotinib, and Methotrexate.
Indication: Treatment of heartburn, GERD, gastritis, and ulcers.
When Not to Use: Esomeprazole is contraindicated in patients with known hypersensitivity to proton pump inhibitors (PPIs). Hypersensitivity reactions, such as angioedema, anaphylaxis, bronchospasm, acute interstitial nephritis, and urticaria, have been reported.
Esomax Capsules Precautions:
Precaution: Daily long-term use (e.g., longer than 3 years) may lead to malabsorption or a deficiency of cyanocobalamin.
Esomax Capsules Warnings:
Warning 1: Hypomagnesemia has been reported rarely with prolonged treatment with PPIs.
Warning 2: Long-term and multiple daily dose PPI therapy may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist, or spine.
Warning 3: Avoid concomitant use of Esomeprazole with Clopidogrel.
Esomax Capsules Additional Information:
Pregnancy Category: Always consult your physician before using any medicine.
Storage (YES/NO): Store this medicine at room temperature, away from direct light and heat.
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