Betaderm 0.1% (Betamethasone) Cream

Betamethasone, a potent synthetic corticosteroid, primarily reduces inflammation by suppressing the release of inflammatory mediators. It inhibits the production of various pro-inflammatory cytokines and reduces the activity of immune cells, leading to decreased redness, swelling, and itching. Neomycin, an aminoglycoside antibiotic, works by binding to bacterial ribosomes, disrupting protein synthesis, and ultimately killing bacteria. This combination allows for the management of skin conditions that exhibit both inflammation and potential bacterial infection. Neomycin helps control bacterial growth, while betamethasone addresses the inflammatory component, making the cream effective for treating infected eczema, dermatitis, and other skin conditions as advised by healthcare professionals.

Betamethasone, Neomycin

Corticosteroid-Antibiotic Combination

Cream

The following are the uses of Betamethasone, Neomycin Cream:

• Used for reducing inflammation and treating skin conditions like eczema, psoriasis, and dermatitis.
• Used for managing skin irritation and itching caused by insect bites, allergic reactions, or minor skin injuries.
• Used to treat skin infections and prevent bacterial growth, especially in cases of infected eczema or wounds.
• Used for relieving symptoms of itching and redness associated with various skin issues.
• Used for promoting skin healing and reducing the risk of infection in minor skin injuries.
• Used for providing temporary relief from skin discomfort and inflammation.
• Used as a short-term treatment to control acute flare-ups of skin conditions.
• Used for improving the overall appearance and comfort of affected skin areas.

To be used as per doctor’s prescription

In the case of an overdose of Betamethasone and Neomycin Cream, it is important to note that topical application is less likely to cause severe side effects compared to ingestion. However, excessive use can lead to skin irritation, redness, and a burning sensation. If ingested, symptoms may include nausea, vomiting, and in severe cases, difficulty breathing. It is crucial to seek medical advice if an overdose is suspected, especially if there are any concerning symptoms.

In the case of a missed dose of Betamethasone, Neomycin Cream, it is important to apply the medication as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply extra cream to make up for the missed dose. However, if you frequently miss doses, inform your healthcare professional, as they may provide guidance on how to manage your treatment plan effectively. It is crucial to maintain a consistent application schedule for optimal results.

To apply Betamethasone, Neomycin Cream, clean and dry the affected area, then gently massage a thin layer of the cream onto the skin, ensuring coverage of the entire affected area, and follow the prescribed frequency and duration of application as directed by your healthcare provider.

Following are the conditions/situations when Betamethasone, Neomycin Cream should not be used:

• Must not be used in individuals with a known allergy or hypersensitivity to Betamethasone, Neomycin, or any other corticosteroids or antibiotics.
• Avoid using on skin areas with viral infections such as herpes, chickenpox, or shingles.
• Not suitable for individuals with bacterial infections that are not responding to treatment.
• Should not be applied to open wounds or broken skin.
• Contraindicated in individuals with skin conditions like rosacea, perioral dermatitis, or skin ulcers.
• Avoid using in patients with skin conditions caused by vaccination, or if the skin is showing signs of atrophy due to previous corticosteroid use.
• Not recommended for individuals with a history of skin reactions after vaccination.
• Do not use on skin areas with tuberculosis infections.
• Avoid using on skin with fungal infections like ringworm or athlete’s foot.

The side effects of Betamethasone, Neomycin Cream may include:

• Skin irritation or itching at the application site
• Thinning of the skin
• Redness or discoloration of the skin
• Allergic reactions (such as rash, hives, or itching)
• Folliculitis (inflammation of hair follicles)
• Acne or pimples
• Burning or stinging sensation
• Delayed wound healing

Following are the precautions and warnings for Betamethasone, Neomycin Cream:

• Avoid using the cream on the face, underarms, or groin area unless directed by a healthcare professional, as these areas are more sensitive.
• Do not use the cream for extended periods without medical supervision, as prolonged use can lead to skin thinning and other adverse effects.
• Wash your hands thoroughly before and after applying the cream to avoid accidental contact with the eyes and mouth.
• Discontinue use and seek medical attention if you experience severe irritation, redness, or allergic reactions.
• Keep the cream out of reach of children and pets to prevent accidental ingestion.
• Inform your doctor if you have existing skin conditions, infections, or a history of allergies before using this medication.
• Do not cover the treated area with bandages or tight clothing, as this may increase the risk of side effects.

Following are the drug interactions for Betamethasone, Neomycin Cream:

• Topical corticosteroids, including betamethasone, may increase the systemic absorption of other drugs due to their vasoconstrictive effect.
• Neomycin, a component of the cream, can cause nephrotoxicity and ototoxicity, especially when used with other aminoglycosides, furosemide, or ethacrynic acid.
• The cream may interact with oral anticoagulants, such as warfarin, and affect blood clotting.
• Combining with other topical medications may increase the risk of local adverse reactions.
• It may reduce the effectiveness of live virus vaccines due to immunosuppression.
• The cream could enhance the systemic effects of hypoglycemic agents or antidiabetic drugs.
• Use with caution alongside nonsteroidal anti-inflammatory drugs (NSAIDs), as it may increase the risk of gastrointestinal bleeding.

Following are the food interactions for Betamethasone, Neomycin Cream:

• Betamethasone can cause increased appetite and weight gain, so it is advisable to maintain a balanced diet and monitor calorie intake.
• Avoid excessive salt consumption as Betamethasone can cause sodium retention, leading to increased blood pressure.
• Limit or avoid foods and beverages containing caffeine, such as coffee, tea, and energy drinks, as they may worsen insomnia, a potential side effect of Betamethasone.
• Consuming alcohol is generally not recommended when using Betamethasone, as it may increase the risk of gastrointestinal issues and other side effects.
• Neomycin, when absorbed systemically, can affect kidney function. Avoid excessive protein intake, as high protein diets may put additional strain on the kidneys.
• No specific food restrictions are associated with Neomycin’s topical use, but maintaining a healthy diet is advisable for overall skin health.
• While not a direct food interaction, some individuals may experience gastrointestinal side effects like nausea or stomach upset, which can impact food choices and tolerance.
• Always follow your healthcare provider’s advice regarding dietary considerations and any specific instructions related to the use of Betamethasone, Neomycin Cream.

Betamethasone, Neomycin Cream should be stored in a cool and dry place, preferably at room temperature, ensuring it is kept away from direct sunlight and moisture. It is crucial to store the cream in its original container, tightly sealed, to maintain its integrity and prevent contamination. Avoid extreme temperatures by not placing it near heat sources like radiators or stoves. Always check the expiration date before use, and if the cream has passed its expiry, do not use it and dispose of it carefully. For proper disposal, consult a pharmacist or healthcare professional, and never flush the cream down the toilet or drain. Keep the cream out of children’s reach to prevent accidental application or ingestion.