How it works
It works by binding to the receptors and inhibits release of the chemical substances that cause psychotic symptoms.
Side effects
Major & minor side effects for Neoris tablet 2 mg 10’s
- Aggression or anger severe
- Loss of balance control severe
- Changes in vision severe
- Skin rash severe
- Back pain severe
- Changes in pattern of speech severe
- Confusion severe
- Dizziness severe
- Loss of appetite severe
- Constipation
- Dry mouth
- Weight gain
- Body pain
- Decrease in libido
Uses of Neoris tablet 2 mg 10’s
What is it prescribed for?
- Schizophrenia
Neoris tablet 2 mg 10’s is used in the treatment of Schizophrenia. Delusions, hallucinations, reduced speaking are some of the symptoms of Schizophrenia.
- Bipolar disorder
Neoris tablet 2 mg 10’s is used in the treatment of bipolar disorder. Unusual shifts in the mood like hyperactivity and tiredness are some of the symptoms of Bipolar disorder.
- Autism
Neoris tablet 2 mg 10’s is used in the treatment of autism. Lack of social interaction, inability to speak and repetitive movements are some of the symptoms of Autism.
Concerns
Frequently asked questions
- Onset of action
The peak effect of this medicine is observed within 1 hour of oral administration.
- Duration of Effect
The effect of this medicine lasts for a duration of 9 hours in extensive metabolizers and 1 to 2 days in poor metabolizers.
- Safe with Alchohol?
Consumption of alcohol with this medicine is not recommended as it can result in dizziness and difficulty in concentration. Avoid activities that need mental alertness like driving and operating machinery.
- Is it habit forming?
No habit forming tendency has been reported
- Usage in pregnancy?
This medicine is not recommended for pregnant women. Use only if clearly needed when no safer alternative is available.
- Usage while breast-feeding?
This medicine is known to be excreted through human breast milk. It is not recommended for breastfeeding women. Use only if clearly needed when no safer alternative is available.
When not to use?
Allergy
Avoid if you have a known allergy to Neoris tablet 2 mg 10’s or any other antipsychotics.
Warnings
Pregnancy
This medicine is not recommended for pregnant women. Use only if clearly needed when no safer alternative is available.
Breast-feeding
This medicine is known to be excreted through human breast milk. It is not recommended for breastfeeding women. Use only if clearly needed when no safer alternative is available.
Dementia- related psychosis
Neoris tablet 2 mg 10’s is not approved for use in patients with dementia-related psychosis due to the increase risk of death.
Neuroleptic Malignant Syndrome
Neoris tablet 2 mg 10’s should be discontinued immediately if the patient develops Neuroleptic Malignant Syndrome characterized by an increase in the body temperature, muscle rigidity, altered consciousness.
Tardive dyskinesia
Neoris tablet 2 mg 10’s may cause involuntary movements of tongue, lips, and face. Inform the doctor if you have these symptoms. Gradual dose reduction or discontinuation of the medicine should be considered.
Diabetes and Dyslipidemia
Neoris tablet 2 mg 10’s may increase the blood glucose levels and lipids levels in the body. Assess these parameters before initiation of the treatment and regular monitoring of blood glucose and body weight is necessary.
Seizures
Neoris tablet 2 mg 10’s is used with caution in the patients with a history of seizures or with conditions that lower the seizure threshold
Pediatric use
The safety and effectiveness of Neoris tablet 2 mg 10’s is not established in the children with schizophrenia who are less than 13 years of age and bipolar disorder who are less than 10 years of age.
Elderly population
Neoris tablet 2 mg 10’s is used with caution in the elderly population due to the increased risk of orthostatic hypotension and kidney injury.
Dosage
- Missed Dose
Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
- Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
Interactions
Interaction with Medicines
- Clozapine severe
- Tramadol severe
- Antidiabetic medicines moderate
- Antihypertensives moderate
- Levodopa moderate
Disease interactions
- severe
This medicine is not recommended in the patients with dementia-related psychosis as it increases the risk of heart diseases like heart failure and infectious diseases like pneumonia. An alternate medicine should be considered based on the clinical condition.
General Instructions
Take Neoris tablet 2 mg 10’s with or without food. Do not take in larger amounts than advised. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine without consulting your doctor as it may cause withdrawal symptoms.
Other details
- Food timings: Information not available
- Administration time: Information not available
- Sleep inducing: Information not available
References
- practo.com – Risperidone [Internet]. Available from: https://www.practo.com/medicine-info/risperidone-245-api [cited 31 August 2019]. 20 Mar 2017
- drugs.com – Risperidone [Internet]. Available from: https://www.drugs.com/risperidone.html [cited 31 August 2019]. Jul 1, 2019
- dailymed.nlm.nih.gov – RISPERIDONE [Internet]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1c3250f3-d291-4280-97d5-da3bb171e2b6#section-2 [cited 31 August 2019]. N/A
- medscape.com – risperidone [Internet]. Available from: https://reference.medscape.com/drug/perseris-risperdal-consta-risperidone-342986 [cited 31 August 2019]. N/A
How to use Neoris tablet 2 mg 10’s
Administered by IM into the upper outer quadrant of the gluteal area. Injection should alternate between the two buttocks. Reconstitute with provided diluent only. Do not combine two different dosage strengths into one single administration. It should be administered every 2 weeks by deep IM deltoid or gluteal injection. Each injection should be administered by an expert using an enclosed safety needle. For deltoid administration, use the 1-inch needle, alternating injection between the 2 arms. For gluteal administration, use the 2-inch needle, alternating between the 2 buttocks. Do not administer IV.
Stability: After reconstitution, store at room temperature and use within 6 hours.
UNLICENSED USE
Children: ORAL: Acute and chronic psychosis: 12-18 yr, 2 mg in 1-2 divided doses on first day then 4 mg in 1-2 divided doses on second day (slower titration appropriate in some children), usual range 4-6 mg/day; doses above 10 mg daily only if benefit considered to outweigh risk, max 16 mg/day.
Short-term monotherapy of mania in bipolar disorder: 12-18 yr, initially 500 mcg once daily adjusted in steps of 0.5-1 mg daily according to response, usual dose 2.5 mg daily in 1-2 divided doses, max 6 mg/day.
Short-term treatment of severe aggression in autism: Over 5 yr and 15-20 kg, 250 mcg daily increased if necessary after at least 4 days to 500 mcg/day, thereafter increased by 250 mcg/day at 2 wk intervals to max 1 mg daily; Over 5 yr and over 20 kg, 500 mcg daily increased if necessary after at least 4 days to 1 mg/day; thereafter increased by 500 mcg daily at 2-wk intervals, max daily dose 2.5 mg if under 45 kg; max daily dose 3 mg if over 45 kg.
what are the adverse effects of Neoris tablet 2 mg 10’s?
Orthostatic hypotension, reflex tachycardia, extra-pyramidal symptoms. Galactorrhoea, menstrual disturbance. Sexual dysfunction, insomnia, anxiety, agitation, headache, fatigue, dizziness, impaired concentration, weight gain gastrointestinal disturbance, rhinitis, rash, blurred vision. Rarely, neuroleptic malignant syndrome, water intoxication with hyponatraemia, seizures.
What happens if I miss a dose of Neoris tablet 2 mg 10’s?
Adults: ORAL: Antipsychotics: Schizophrenia: Over 15 yr, day one, 1 mg twice daily; day two, 2 mg twice daily; day three 3 mg twice daily. Max 8 mg twice daily. Elderly: Initially 0.5 mg twice daily increasing in 0.5 mg increments to 1-2 mg twice daily.
Bipolar Disorder: Acute Manic & Mixed Episodes: Monotherapy or adjunct therapy with lithium or valproate: Initial: 2-3 mg daily. Titrate: Increase by 1 mg daily. Max 6 mg/day.
Adults: INJECTION: By deep IM injection into the deltoid or gluteal muscle, Patients taking oral risperidone up to 4 mg daily, initially 25 mg IM every 2 wk; Patients taking oral risperidone over 4 mg daily, initially 37.5 mg IM every 2 wk; dose adjusted at intervals of at least 4 wk in steps of 12.5 mg to max 50 mg IM every 2 wk.
Children: ORAL: Short-term treatment (up to 6 wk) of persistent aggression in conduct disorder: 5-18 yr and body-weight under 50 kg, initially 250 mcg once daily increased according to response in steps of 250 mcg on alternate days, usual dose 500 mcg daily (up to 750 mcg once daily has been required); 5-18 yr and body-weight over 50 kg, initially 500 mcg once daily increased according to response in steps of 500 mcg on alternate days, usual dose 1 mg daily (up to 1.5 mg once daily has been required).
One of the following licensed pharmacy from the nearest location will deliver Neoris tablet 2 mg 10’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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