Trisil Plus Suspension (Aluminium+Magnesium+Simeticone)

Aluminum Hydroxide, Magnesium Hydroxide, and Simethicone work together to provide relief from various gastrointestinal symptoms. Aluminum and Magnesium Hydroxides are antacids that neutralize excess stomach acid by reacting with hydrochloric acid, raising the gastric pH. This helps to alleviate acid-related discomfort and protect the stomach lining. Simethicone, an anti-foaming agent, reduces gas accumulation in the stomach and intestines by breaking up gas bubbles, allowing for easier expulsion. This combination helps to relieve symptoms such as heartburn, indigestion, and excessive gas, providing a soothing effect on the gastrointestinal tract.

Aluminium Hydroxide, Magnesium Hydroxide, Simethicone

Antacid, Antiflatulent

Suspension

The following are the uses of Aluminium Hydroxide, Magnesium Hydroxide, Simethicone Syrup/Suspension:

• Used for relieving heartburn, acid indigestion, sour stomach, and other gastrointestinal issues.
• Used as an antacid to neutralize excess stomach acid.
• Effective in treating symptoms of peptic ulcer disease and gastroesophageal reflux disease (GERD).
• Helps reduce stomach acid to provide relief from acid-related discomfort.
• Used to treat diarrhea by slowing down the movement of the gut.
• Can be used to manage symptoms of an upset stomach during pregnancy.
• Provides relief from bloating, gas, and abdominal discomfort caused by excess gas.
• Safe for long-term use in managing chronic acid-related conditions.

To be taken as per doctor’s prescription

In the case of an overdose of Aluminium Hydroxide, Magnesium Hydroxide, and Simethicone Syrup/Suspension, gastrointestinal symptoms may occur, including nausea, vomiting, and diarrhea. These symptoms are typically mild and self-limiting. However, if a large amount is ingested, more severe effects such as muscle weakness, irregular heartbeat, and seizures may develop. Prompt medical evaluation is advised to ensure appropriate supportive care and monitoring.

In the case of a missed dose of Aluminum Hydroxide, Magnesium Hydroxide, and Simethicone Syrup/Suspension, it is generally advised to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. Consult your healthcare provider if you frequently miss doses or are unsure about how to manage missed doses.

To administer Aluminium Hydroxide, Magnesium Hydroxide, and Simethicone Syrup/Suspension, shake the bottle vigorously, then accurately measure the prescribed dose using a measuring cup or oral syringe; administer the medication orally, following the dosage instructions provided by your healthcare professional or as indicated on the medication label, typically taken as directed, regardless of mealtimes.

Following are the conditions/situations when Aluminium Hydroxide, Magnesium Hydroxide, and Simethicone Syrup/Suspension should not be used:

• Not suitable for individuals with a known allergy or hypersensitivity to any of the active ingredients, including Aluminium Hydroxide, Magnesium Hydroxide, or Simethicone.
• Should not be used in patients with severe kidney disease or impaired kidney function, as it may lead to aluminum accumulation.
• Contraindicated in patients with severe constipation or bowel obstruction, as it can worsen these conditions.
• Not recommended for individuals with a history of gastrointestinal bleeding or perforation.
• Should be avoided in patients with severe dehydration, as it may affect electrolyte balance.
• Not suitable for infants or children under 6 years of age without medical advice, as the dosage may need to be adjusted for younger patients.
• Should not be used in individuals with a known intolerance to sorbitol or other ingredients in the syrup/suspension.
• Avoid using if you have a condition that requires a low-aluminum diet, as prescribed by your doctor.

The side effects of Aluminium Hydroxide, Magnesium Hydroxide, and Simethicone Syrup/Suspension may include:

• Constipation
• Diarrhea
• Nausea and vomiting
• Stomach pain or cramps
• Dry mouth
• Tiredness or fatigue
• Headache
• Mild skin rash or itching

Following are the precautions and warnings for Aluminium Hydroxide, Magnesium Hydroxide, and Simethicone Syrup/Suspension:

• Do not use in patients with known allergies to aluminium, magnesium, simethicone, or any other ingredients in the suspension.
• This medication should be used with caution in patients with kidney disease or those on a low-phosphate diet, as it may affect kidney function and phosphate levels.
• Avoid excessive use as it may cause diarrhea, abdominal pain, and dehydration.
• Do not use for more than 2 weeks without consulting a healthcare professional.
• Patients with phenylketonuria (PKU) should be aware that some brands may contain phenylalanine.
• Elderly patients may be more sensitive to the effects and should be monitored closely for side effects.
• Pregnant and breastfeeding women should consult their doctor before taking this medication as it may affect fetal bone development and could pass into breast milk.

Following are the drug interactions for Aluminium Hydroxide, Magnesium Hydroxide, Simethicone Syrup/Suspension:

• May decrease absorption of tetracycline antibiotics, fluoride, and fluoroquinolones when taken concurrently.
• Can reduce the absorption of levothyroxine, a thyroid medication, when taken together.
• Concomitant use with bisphosphonates may decrease their effectiveness due to reduced absorption.
• May decrease the absorption of iron supplements, leading to reduced efficacy.
• When combined with phenytoin, an anti-seizure medication, it can decrease the absorption of phenytoin.
• Interactions with other drugs that require an acidic environment for absorption, such as azole antifungals, may occur.
• The syrup/suspension may contain sugar, which should be considered when used with diabetes medications.

Following are the food interactions for Aluminium Hydroxide, Magnesium Hydroxide, Simethicone Syrup/Suspension:

• Avoid excessive consumption of high-phosphorus foods like dairy products, meat, and beans, as Aluminium Hydroxide can bind with dietary phosphorus, reducing its absorption and potentially leading to nutrient deficiencies.
• Limit your intake of high-fat meals as Magnesium Hydroxide can bind with dietary fats, reducing its absorption and affecting the effectiveness of the medication.
• Avoid or limit the use of chocolate and caffeine-containing beverages as they can increase stomach acid production, potentially reducing the efficacy of the medication.
• Alcohol should be avoided as it can irritate the stomach lining and potentially worsen gastrointestinal symptoms, reducing the effectiveness of the medication.
• It is generally recommended to take this medication on an empty stomach, at least 1 hour before or 2 hours after meals, for optimal absorption.
• Avoid consuming antacids with carbonated beverages as the carbonation can increase gas and bloating, which Simethicone is intended to relieve.
• It is advisable to follow a balanced diet and stay well-hydrated to support the overall effectiveness of the medication and maintain good digestive health.

Aluminium Hydroxide, Magnesium Hydroxide, and Simethicone Syrup/Suspension should be stored in a controlled environment, specifically a cool and dry place, preferably at room temperature, away from direct sunlight and moisture. Ensure the medication is tightly sealed within its original container to maintain its integrity and prevent contamination. Avoid storage in bathrooms or near heat sources like stoves, as temperature fluctuations can impact the medication’s effectiveness. Always adhere to proper disposal practices; do not flush or pour down the drain. Consult a pharmacist or healthcare professional for appropriate disposal methods, and keep the medication out of children’s reach to prevent accidental ingestion.

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Following are the quick tips for Aluminium Hydroxide, Magnesium Hydroxide, Simethicone Syrup/Suspension:

• Always follow the dosage instructions provided by your healthcare professional.
• Shake the bottle vigorously to ensure a uniform mixture before each use.
• Administer the syrup with a glass of water, avoiding tea, coffee, or dairy for better absorption.
• Maintain a consistent schedule by taking the medication at the same time daily.
• To reduce potential stomach discomfort, consider taking it with food or post-meal.
• Store the medication safely, out of children’s reach, to prevent accidental ingestion.
• Do not share your medication with others, even if their symptoms appear similar.