Prazol Capsules 40Mg (1 Strip = 7 Capsules)

Requires Prescription: Yes

Generics: Omeprazole

Used For: Gastroesophageal Reflux Disease (GERD)

How It Works:

Omeprazole inhibits gastric acid secretion by irreversibly blocking the hydrogen/potassium adenosine triphosphatase (H+/K+ ATPase) enzyme system in gastric parietal cells. This action reduces both basal and stimulated acid secretion, regardless of the stimulus.

Prazol Capsules Usage and Safety

Dosage: Omeprazole

Side Effects:

Common:

Central Nervous System: Headache

Gastrointestinal: Diarrhea, constipation, abdominal pain, nausea/vomiting, flatulence

Uncommon:

Central Nervous System: Dizziness, paraesthesia, somnolence, insomnia, vertigo

Hepatic: Increased liver enzymes

Skin: Rash, pruritis, urticaria

Other: Malaise

Rare:

Central Nervous System: Reversible mental confusion, agitation, aggression, depression, hallucinations (mainly in severely ill patients)

Endocrine: Gynecomastia

Drug Interactions:

Consult your physician or pharmacist for interactions with drugs such as ketoconazole, itraconazole, diazepam, citalopram, imipramine, clomipramine, phenytoin, atazanavir, digoxin, clopidogrel, posaconazole, erlotinib, saquinavir, tacrolimus, methotrexate, clarithromycin, and CYP2C19 or CYP3A4 inhibitors (e.g., rifampicin, St John’s Wort).

Indication:

Gastro-Esophageal Reflux Disease (GERD):

Treatment of erosive reflux esophagitis

Long-term management of healed esophagitis to prevent relapse

Symptomatic treatment of GERD

When Not to Use:

Contraindicated in patients with hypersensitivity to any component of the formulation or to substituted benzimidazoles

Must not be used with nelfinavir

Prazol Capsules Precautions:

Precaution:

Omeprazole may reduce vitamin B12 absorption due to decreased gastric acid. Monitor patients with risk factors for vitamin B12 deficiency during long-term therapy.

Prazol Capsules Warnings

Warning 1:

Exclude malignancy in cases of suspected gastric ulcer, as omeprazole treatment may alleviate symptoms and delay diagnosis.

Warning 2:

Long-term use and high doses of proton pump inhibitors may modestly increase the risk of hip, wrist, and spine fractures, particularly in the elderly or those with other risk factors.

Warning 3:

Reduce the dose in patients with impaired hepatic function, as omeprazole’s bioavailability and half-life may increase.

Additional Information:

Pregnancy Category:

Consult your physician before using any medicine.

Storage:Store at room temperature, away from direct light and heat.